A positive-selection function for microRNA: an adaptor hypothesis revisited

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A positive-selection function for microRNA: an adaptor hypothesis revisited.

A hypothesis for coding different combinations of mRNA segments by a novel postulated function of microRNAs (miRNA) is presented. In this hypothesis, miRNA act as both coding adaptors and ligating enzymes. This hypothesis postulates an enzyme-substrate intermediate comprising a RNA triplex structure consisting of a miRNA adaptor and two mRNA configured as two turns of an A-form RNA helix. Postu...

متن کامل

HYPOTHESIS TESTING FOR AN EXCHANGEABLE NORMAL DISTRIBUTION

Consider an exchangeable normal vector with parameters ????2, and ?. On the basis of a vector observation some tests about these parameters are found and their properties are discussed. A simulation study for these tests and a few nonparametric tests are presented. Some advantages and disadvantages of these tests are discussed and a few applications are given.

متن کامل

The hygiene hypothesis revisited

To date, a large body of data supports the hygiene hypothesis. However, the explanation of the relationship of autoimmune and allergic diseases with a decrease in microbial load still seems insufficient. Here, an attempt is made at interpreting the available data in terms of a new perspective on infection and immunity.

متن کامل

The British hypothesis revisited.

Forty years ago, British investigators developed the hypothesis that recurrent bronchial infections were the reason that some smokers developed progressive airways obstruction and other did not [1]. The classical studies of FLETCHER et al. [2] were designed to test this proposition. They carried out a prospective study of working males, noting the frequency of respiratory infections, sputum qua...

متن کامل

Hypothesis test for synchronization: twin surrogates revisited.

The method of twin surrogates has been introduced to test for phase synchronization of complex systems in the case of passive experiments. In this paper we derive new analytical expressions for the number of twins depending on the size of the neighborhood, as well as on the length of the trajectory. This allows us to determine the optimal parameters for the generation of twin surrogates. Furthe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Reproductive BioMedicine Online

سال: 2006

ISSN: 1472-6483

DOI: 10.1016/s1472-6483(10)61000-0